Early Endosome

In Tetrahymena, Early Endosomes serve a crucial role in endocytosis as the sorter of internalized proteins and lipids retrieved from the extracellular environment. Once inside the Early Endosome, these resources are separated into distinct areas of the endosome where they will be sent to different parts of the cell for various purposes. For Tetrahymena, coated vesicles from Parasomal sacs are also known to fuse with the Early Endosomes to deliver nutrients.

Articles:

Cole, E. S., Maier, W., Joachimiak, E., Jiang, Y. Y., Lee, C., Collet, E., … & Gaertig, J. (2023). The Tetrahymena bcd1 mutant implicates endosome trafficking in ciliate, cortical pattern formation. Molecular biology of the cell, 34(8), ar82.

Jovic, M., Sharma, M., Rahajeng, J., & Caplan, S. (2010). The early endosome: a busy sorting station for proteins at the crossroads. Histology and histopathology, 25(1), 99–112.

Media:

Image illustrates the biogenesis of exosomes and the inward budding of early endosomes to form vesicles to carry proteins and RNA. Credited to Law ZJ, Khoo XH, Lim PT, Goh BH, Ming LC, Lee WL and Goh HP under the Creative Commons Attribution 4.0 International license.

Early Endosomes
Early Endosome Early Endosome Early Endosome Lipid Droplet Lipid Droplet Mucocyst Parasomal Sac Parasomal Sac Coated Vesicle Coasted Vesicle Coasted Vesicle Coasted Vesicle Coated Vesicle

Early Endosome

Early Endosome

Early Endosome

Image depicts the cross section of a Tetrahymena cell and the cell structures of interest within it. Credited to Professor Richard Allen and his Image Collection, permission to use image collection granted by Hawaii University.

Genes, Proteins, and Mutations: